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DNA and RNA / by Hall, Linley Erin.(CARDINAL)470325;
Includes bibliographical references and index.Introduction to DNA -- DNA replication -- Introduction to RNA -- Transcription and translation -- Gene regulation -- Mutations for good and bad -- Recombinant DNA.
Subjects: DNA; RNA;
Available copies: 2 / Total copies: 2
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The catalyst : RNA and the quest to unlock life's deepest secrets / by Cech, Thomas,author.(CARDINAL)887928;
Includes bibliographical references (pages 251-280) and index.Introduction: The age of RNA -- Part I: The search. The messenger -- Splice of life -- Going it alone -- The shape of a shapeshifter -- The mothership -- Origins -- Part II: The cure. Is the fountain of youth a death trap? -- As the worm turns -- Precise parasites, sloppy copies -- RNA versus RNA -- Running with scissors -- Epilogue: The future of RNA."One of Literary Hub's Most Anticipated Books of 2024. Exploring the most transformative breakthroughs in biology since the discovery of the double helix, a Nobel Prize-winning scientist unveils the RNA age. For over half a century, DNA has dominated science and the popular imagination as the "secret of life." But over the last several decades, a quiet revolution has taken place. In a series of breathtaking discoveries, the biochemist Thomas R. Cech and a diverse cast of brilliant scientists have revealed that RNA--long overlooked as the passive servant of DNA--sits at the center of biology's greatest mysteries: How did life begin? What makes us human? Why do we get sick and grow old? In The Catalyst, Cech finally brings together years of research to demonstrate that RNA is the true key to understanding life on Earth, from its very origins to our future in the twenty-first century. A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health. We learn how RNA--once thought merely to transmit DNA's genetic instructions to the cell's protein-making machinery--may have jump-started life itself, and how, at the same time, it can cut our individual lives short through viral diseases and cancer. We see how RNA is implicated in the aging process and explore the darker depths of the supposed fountain of youth, telomerase. And we catch a thrilling glimpse into how RNA-powered therapies--from CRISPR, the revolutionary tool that uses RNA to rewrite the code of life, to the groundbreaking mRNA vaccines that have saved millions during the pandemic, and more--may enable us to improve and even extend life beyond nature's current limits. Written by one of our foremost scientists, The Catalyst is a must-read guide to the present and future of biology and medicine."--
Subjects: Informational works.; RNA.; Genomics.;
Available copies: 16 / Total copies: 18
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The double life of RNA [videorecording] / by Bruns, Peter,(Peter J.); Cech, Thomas.; Liu, Dennis W. C.(CARDINAL)327036; Sutherland, Ann DeStefano.; Howard Hughes Medical Institute.(CARDINAL)274867; Sutherland Media Productions.(CARDINAL)332483;
Interactive features: New science of RNA interference -- Telomeres ten years after -- Diversity of RNA structures.Lecture 1. Catalysis, chemical and biochemical -- Lecture 2. RNA as an enzyme: discovery, origins of life, and medical possibilities -- Lecture 3. How to accelerate a reaction 100,000,000,000 times using only RNA -- Lecture 4. Life at the end of the chromosome: another RNA machine.Video segments from 2003: Enzymes that are not proteins: the discovery of ribozymes (20 min.) -- Dr. Thomas Cech on becoming a scientist (10 min.) -- NOVA scienceNOW on RNA! (16 min.).Executive producers of the DVD, Thomas R. Cech, Peter J. Bruns; producer, Dennis W.C. Liu.The four lectures were produced by Sutherland Media Productions for the Howard Hughes Medical Institute; producer Ann DeStefano Sutherland.Lecturer, Thomas R. Cech.Four lectures (60 min. each) presented in 1995 by Dr. Thomas R. Cech explain the role of RNA in cellular biology. Dr. Cech also discusses other implications of RNA catalysis.The DVD also includes 3 additional video segments from 2003, 3 hands-on experiment demonstrations, and 3 interactive slideshow features.DVD.
Subjects: Films for the hearing impaired.; Catalytic RNA.; Films for the hearing impaired.; RNA.; Telomere.; RNA.; Molecular Biology.; Research.;
Available copies: 1 / Total copies: 1
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Junk DNA : a journey through the dark matter of the genome / by Carey, Nessa,author.(CARDINAL)399349;
Includes bibliographical references (pages 289-328) and index.An introduction to genomic dark matter -- Why dark matter matters -- When dark matter turns very dark indeed -- Where did all the genes go? -- Outstaying an invitation -- Everything shrinks when we get old -- Two is the perfect number -- Painting with junk -- Playing the long game -- Adding colour to the dark matter -- Why parents love junk -- Junk with a mission -- Switching it on, turning it up -- No man's land -- Project ENCODE : Big Science comes to junk DNA -- Headless queens, strange cats, and portly mice -- Lost in translation -- Why LEGO is better than Airfix -- Mini can be mighty -- The drugs do work (sometimes) -- Some light in the darkness -- Appendix. Human diseases in which junk DNA has been implicated.For decades after the indentification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Our increasing knowledge of junk DNA has led to innovative research and treatment approaches that may finally ameliorate some of these conditions. Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word "gene" and have engendered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. We are only now unlocking the secrets of junk DNA, and Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field. --
Subjects: Genomics.; Human genome.; Eukaryotic cells.; Recombinant DNA.; Insertion elements, DNA.; Non-coding RNA.; Gene therapy.;
Available copies: 2 / Total copies: 2
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The messenger : Moderna, the vaccine, and the business gamble that changed the world / by Loftus, Peter(Peter D.),author.;
Includes bibliographical references and index.Prologue. Disease X -- Changing the Fate -- If This Is True -- Kendall Square -- Feeding the Beast -- Broke Offer -- No Boundaries -- mRNA- -- More Money -- Warp Speed -- Hold On, Help Is On the Way -- Politics Protocols and Patents -- The Power of Science -- Evidence -- Happy Tears -- Delta -- Just the Beginning."At the start of 2020, Moderna was a waning biotech unicorn, still years away from delivering its first product despite a decade of development of a potentially breakthrough innovation: using RNA to combat disease. Investors were getting antsy or, worse, skeptical. Then the coronavirus pandemic hit, and Moderna became a central player in a global drama--a David to pharma's Goliaths--turning its technology toward breaking the global grip of the terrible disease. By year's end, as the outbreak was at its worst, Moderna delivered one of the world's first Covid-19 vaccines, with a stunningly high rate of protection. The achievement not only offered the world a way out of a crippling pandemic but also validated Moderna's gene-based technology, transforming the company into a global industry power, swelling its market value on its prospects for new drugs and vaccines for years to come. Biotech, and the venture capital community that fuels it, will never be the same. Wall Street Journal reporter Peter Loftus, part of a Pulitzer Prize-finalist reporting team and 25-year veteran reporter in the pharmaceutical and biotech industries, brings the inside story of how Moderna went all in on a single revolutionary idea; of quiet research with unknown consequence; of the evolution of a cutting-edge American innovation, industry, and economy--decades in the making--that led to one of the great gambles in business history"--
Subjects: Moderna (Firm); Vaccines industry; Pharmaceutical biotechnology industry; Messenger RNA.;
Available copies: 2 / Total copies: 2
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12 revolutionary discoveries that could change everything [videorecording] / by Helmuth, Laura,speaker.; Scientific American, inc.,sponsor.(CARDINAL)325071; Teaching Company,production company.(CARDINAL)349444;
Lecturer: Laura Helmuth, editor in chief of Scientific American."We are living in a golden age of scientific breakthroughs and technological advancements. From the messenger RNA (mRNA) technology deployed in the COVID-19 vaccines to new research into the biology of lichens to new theories about the inner workings of black holes, the 21st century has given us an exciting new understanding of ourselves, our world, and our universe. Now, you have the chance to dig into 12 of the most fascinating and important scientific advancements and paradigm shifts in recent years. Unexpected, consequential, and often counterintuitive, 12 Revolutionary Discoveries That Could Change Everything offers an inspiring introduction to science in the 21st century. Taught by Scientific American editor in chief Laura Helmuth, these 12 eye-opening lectures will satiate even the most inquisitive mind."--Publisher's website.DVD, NTSC.
Subjects: Lectures.; Documentary films.; Educational films.; Informational works.; Nonfiction films.; Video recordings for the hearing impaired.; Discoveries in science.; Biology.; Biological fitness.; RNA targeting.; Brain mapping.; Ocean.; Vikings.; Adjustment (Psychology);
Available copies: 0 / Total copies: 1
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DNA : the master molecule of life / by Stille, Darlene R.(CARDINAL)275009;
Includes bibliographical references (page 47) and index.The master molecule of life -- Genes and DNA -- The genetic code -- RNA and the protein factory -- Making use of DNA.Have you ever wondered why you have brown hair, blue eyes, or freckles? All human beings have basically the same facial structure?two eyes, a nose and a mouth?yet none of us look exactly the same. Our traits are determined by DNA, a chemical that can be found in every organism. Find out where DNA is located and how it helps determine our individual traits.990LAccelerated Reader AR
Subjects: DNA;
Available copies: 3 / Total copies: 3
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Life evolving : molecules, mind, and meaning / by De Duve, Christian.(CARDINAL)324673;
Includes bibliographical references and index.What is life? chemistry -- What is life? information -- Where does life come from? -- How did life arise? the way to RNA -- How did life arise? from RNA to protein-DNA -- How did life arise? the birth of cells -- The history of life -- The invisible world of bacteria -- The mysterious birth of eukaryotes: the problem -- The mysterious birth of eukaryotes: a possible pathway -- The visible revolution -- The arrow of evolution -- Becoming human -- The riddle of the brain -- Reshaping life -- After us, what? -- Are we alone? -- How about God in all that?De Duve shares his thoughts on God and immortality, as well as future evolutionary conjectures, as he explores topics such as the evolution of life from the first cells to complex organisms, the development of language and emotion, and the origins of consciousness.1420L
Subjects: Evolution (Biology); Life (Biology); Life;
Available copies: 2 / Total copies: 2
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Reproduction and genetics / by Eason, Sarah.(CARDINAL)491257;
What is reproduction? -- Asexual reproduction -- Sexual reproduction -- What is genetics? -- The principles of inheritance -- Cells and chromosomes -- RNA and DNA -- Genomes -- Human genetics -- Life cycles -- Human reproduction -- Human development and aging.Lexile not available
Subjects: Human genetics; Human reproduction;
Available copies: 2 / Total copies: 2
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The basics of genetics / by Wanjie, Anne,editor.(CARDINAL)609480;
Includes bibliographical references and index.The revolution in genetics represents one of the most amazing expansions of knowledge in the history of science. Incredible advances such as the mapping of the human genome are continuing to unlock the mysteries of heredity. This title gives students the power to understand this fascinating area of biology by starting with the basics. The science behind each concept is explained with clear text and a wealth of informative illustrations, color images, and sidebars. Biographical material on Gregor Mendel, the first person to describe how traits are passed from generation to generation, shows readers how the genetic revolution began. The text fulfills the requirements of the Common Core by helping readers learn the meaning of key terms as they are used in the context of biology. It also helps readers synthesize textual and visual information into a coherent understanding of genetic processes. Ages 14+Genetics: the study of heredity -- Principles of inheritance -- The process of cell division -- From DNA to RNA to protein -- Understanding genomes -- Concepts in human genetics -- Applying genetic knowledge -- Biography: Gregor Mendel.
Subjects: Genetics.; Heredity.;
Available copies: 3 / Total copies: 6
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Results 1 to 10 of 58 |